Questo sito utilizza solo cookie tecnici per il corretto funzionamento delle pagine web e per il miglioramento dei servizi.
Se vuoi saperne di più o negare il consenso consulta l'informativa sulla privacy.
Proseguendo la navigazione del sito acconsenti all'uso dei cookie.
Se vuoi saperne di più o negare il consenso consulta l'informativa sulla privacy.
Proseguendo la navigazione del sito acconsenti all'uso dei cookie.
Seminario del 2018
2018
16 luglio
The biodiversity that we observe on Earth is ultimately the product of evolutionary forces: natural
selection, mutations, recombination, and random genetic drift jointly shaped the genome of all
living organisms. By employing Next Generation Sequencing techniques, geneticists are now able
to observe patterns of DNA sequence variation at different evolutionary scale and with an
unprecedented level of details.
Coalescent theory represent arguably the most robust mathematical framework describing the
connection between those changes in the genome and the demographic history of a species.
In this seminar, I will introduce the standard coalescent model, how this arises from Poisson
processes and its connection with a simple population genetic model (the Wright-Fisher model).
I will then discuss how can we build more sophisticated models within the coalescent framework
and how we can apply them to reconstruct the evolutionary history of a species and redefine the
species concept itself.